About the vacancy
Production
About Your Next Job
MAT Research is a pioneering company in the field of pyrogen testing, committed to ushering in a new era of ethical and accurate diagnostics. Since 2016, we have been leading the development of the Monocyte Activation Test (MAT), an animal-free alternative to traditional Rabbit Pyrogen Tests. Our ready-to-use MAT kits offer a robust and highly reliable method for detecting a broad range of pyrogens in parenteral drugs. ISO:9001:2015 certified, we uphold the highest standards of quality in all our products and services. By focusing on in-vitro human-based testing, we aim to drastically increase patient safety while saving hundreds of thousands of animal lives each year. We are steadfast supporters of the European Pharmacopoeia's vision to replace animal-based tests with MAT by 2026. For more details, go to our job page.
As we continue to scale, we are looking for a Manufacturing Operator/Technician to join our growing team in Leiden, Netherlands. You will play a vital role in the production, quality assurance, and scale-up of our MAT diagnostic kits. This role is ideal for professionals with a biotech manufacturing background, particularly in immunology-focused production environments.
About Your Next Colleagues
We are a small growing team of 9 dedicated people.
Our team members are adaptable, capable of wearing multiple hats when necessary. But with this flexibility comes a strong sense of responsibility. Every individual owns their role and the results that come with it.
Join a team that's making real change – by enhancing patient safety and saving animal lives.
About Your Tasks and Responsibilities
Your key responsibilities will include:
Manufacturing & Production
Equipment & Process Maintenance
Quality Control & Compliance
Material & Inventory Management
Process Improvement & Reporting
To fulfill these responsibilities, you will:
Execute end-to-end manufacturing processes, including preparation, formulation, and packaging of MAT kits.
Follow Standard Operating Procedures (SOPs), batch records, and Good Manufacturing Practices (GMP) to ensure consistency and quality.
Assist in the scale-up of manufacturing processes, optimising workflow efficiency.
Operate and maintain bioprocessing and immunoassay equipment.
Perform routine calibration, sterilisation, and maintenance of manufacturing tools.
Monitor and troubleshoot production deviations or process inefficiencies.
Conduct in-process quality control tests to ensure product reliability.
Work closely with Quality Assurance (QA) teams to maintain compliance with ISO:9001:2015, GMP, and regulatory requirements.
Maintain accurate batch records and production documentation to ensure traceability.
Prepare, measure, and handle biological materials, PBMCs, reagents, and consumables.
Ensure proper storage conditions and inventory tracking for raw materials and finished products.
Support continuous improvement initiatives to optimise production workflows.
Assist in developing new SOPs, technical documentation, and training materials.
Report deviations and contribute to troubleshooting investigations and corrective actions
About Your Skills and Experience
Job requirements
- Living near Leiden or able to relocate without support.
Bachelor’s (HLO/HBO) or Master’s (University) degree in biological/medical sciences or equivalent, preferably with a strong immunology/cellular background.
Additional certifications in bioprocessing, GMP, or quality control are a plus.
At least 3 years of hands-on experience in biotech, pharmaceutical, or immunology-based manufacturing, PBMC isolations, cellular assays, and analytical-based assays (ELISA, Flow Cytometry) according to regulatory standards such as ICH is a pre.
Familiarity with GMP, ISO:9001, and regulatory compliance for biotech production.
Strong attention to detail with excellent documentation and data recording skills.
Ability to work in a cleanroom or controlled laboratory environment.
Problem-solving mindset with the ability to troubleshoot and improve processes.
Comfortable with inventory and logistics software, capable of managing resources efficiently.
Excellent skills in technical writing and reporting.
Fluent in English; proficiency in Dutch, German, or French is a major plus.
Willing to hit the road for occasional business trips
About Your Benefits
Your compensation will be:
Competitive base salary (Full-time 40 h/week)
25 vacation days + national holidays
Where Molecules Meet Opportunities
Broaden Your Horizons
Be at the forefront of a shift in scientific testing and contribute to a method that detects a wider range of pyrogens than ever before.
As part of the MAT Research team, you'll have the opportunity to grow, learn, and shape the future of ethical pyrogen testing.Grow With Us
Only apply if...
We’re Recruiting high performers! If you have the zeal for science, the drive to make a difference, and the passion to be a part of an evolving and revolutionary field, we want YOU.
Step into the future with MAT Research. Together, we'll create a world where ethical testing is the norm, not the exception.
You are eligible to work in EU
We only accept applicants who are eligible to work in the EU
Contact person
Marianne Bro
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We have developed an improved Monocyte Activation Test (MAT) for pyrogen testing. The MAT serves as the replacement for the Rabbit Pyrogen Test and can be used to test parenteral drugs for endotoxin and non-endotoxin contaminations. Our technology uses cryopreserved pooled PBMC. This has made it possible to develop a MAT with both high sensitivity and robustness, ensuring reliability in the field.
Monocyte Activation Test (MAT) The Monocyte Activation Test (MAT) is a pyrogen test. MAT uses human blood cells to test for a fever reaction, mimicking the human immune reaction.The MAT serves as the replacement for the Rabbit Pyrogen Test and can be used to test parenteral drugs for endotoxin and non-endotoxin contaminations. Our technology uses cryopreserved pooled PBMC. This has made it possible to develop a MAT with both high sensitivity and robustness, ensuring reliability in the field. The MAT kit includes all the required consumables to perform the Monocyte Activation Test, making it convenient to perform. In addition to the kit we provide consulting services and technical support in setting up the MAT in your organisation.