Open for applications

Senior Scientist (Immunology, BioTech)

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About the vacancy

R&D
Immunology
Expert Doctorate (PhD, MD, etc.) Permanent Full time

About Your Next Job

MAT Research is a pioneering company in the field of pyrogen testing, committed to ushering in a new era of ethical and accurate diagnostics. Since 2016, we have been leading the development of the Monocyte Activation Test (MAT), an animal-free alternative to traditional Rabbit Pyrogen Tests. Our ready-to-use MAT kits offer a robust and highly reliable method for detecting a broad range of pyrogens in parenteral drugs. ISO:9001:2015 certified, we uphold the highest standards of quality in all our products and services. By focusing on in-vitro human-based testing, we aim to drastically increase patient safety while saving hundreds of thousands of animal lives each year. We are steadfast supporters of the European Pharmacopoeia's vision to replace animal-based tests with MAT by 2026. For more details, go to our job page.


We're scaling fast and are now seeking a Senior Scientist with deep immunology expertise to accelerate our R&D, support high-impact product development, and ensure operational excellence across manufacturing and QA/QC. This is a high-ownership role in a biotech scale-up environment—ideal for a scientist eager to make meaningful contributions to both the lab and business outcomes.


The ideal candidate will excel in scientific research, regulatory compliance and lab operations. Extensive immunology experience is a hard requirement.



About Your Next Colleagues

We are a small growing team of 9 dedicated people.

Our team members are adaptable, capable of wearing multiple hats when necessary. But with this flexibility comes a strong sense of responsibility. Every individual owns their role and the results that come with it.

Join a team that's making real change – by enhancing patient safety and saving animal lives.


About Your Tasks and Responsibilities

Your key responsibilities will include:

  • Product development and optimisation.

  • Product manufacturing pipeline and delivery processes.

  • Scientific research, innovation and execution.

  • Quality Assurance & Control.

  • Regulatory Compliance.

  • Scientific team performance.

To fulfill these responsibilities, you will:

  • Design and execute high-precision experiments using cutting-edge data analysis tools for groundbreaking results.

  • Streamline lab processes with the lab manager and lab technicians for peak efficiency through continuous optimization.

  • Enforce strict QA/QC standards, upholding impeccable quality in all lab activities.

  • Maintain meticulous experiment records, ensuring unassailable data integrity.

  • Master regulatory compliance by staying current on ISO9001 and industry norms, and conducting regular safety audits. (Potential customers, European Pharmacopoeia and FDA)

  • Synthesise lab data into comprehensive reports, offering actionable insights on efficiency and performance.

  • Organize and provide scientific and technical updates to clients and internal stakeholders on project status.

  • Initiate and execute general process improvements to improve safety, lead time and efficiency.

  • Routinely execution of immunological, cell-based assays and analytical methods.

  • Supervise and lead scientists and lab technicians.

  • Give training on how to perform accurate MAT testing, for clients and external parties.


About Your Skills and Experience

  • Living in the Netherlands near Leiden or able to relocate in the short term.

  • PhD or MSc in Immunology, Immuno-oncology, Immunotherapy, Cell Biology, or related discipline. (PhD strongly preferred) 

  • At least 5+ years of industry experience (Biotech, Pharma, or CRO) in immunology-focused R&D — ideally in a scale-up or high-growth environment.

  • Extensive, hands-on experience in PBMC isolations, cellular assays, and analytical-based assays (ELISA, Flow Cytometry) according to regulatory standards such as ICH. 

  • Strong track record in applied research.

  • Expert-level skills in data analysis software and modern quality management systems.

  • Demonstrated finesse in experimental execution, marked by precision and meticulous attention to detail.

  • Experience in working under quality standards such as GMP/GLP and ISO:9001.

  • Comfortable with inventory and logistics software, capable of managing resources efficiently.

  • Innovative with an entrepreneurial attitude, looking beyond what is possible and known.

  • Self-starter with teamwork skills, adept at juggling priorities to nail deadlines.

  • Willing to hit the road for occasional business trips.

  • Fluent in English; proficiency in Dutch, German, or French is a major plus.


About Your Benefits

Your compensation will be:

  • Competitive base salary (Full-time, 40 hrs/week)

  • Twenty-five vacation days per year and your National Holidays off.


Where Molecules Meet Opportunities

Broaden Your Horizons

Be at the forefront of a shift in scientific testing and contribute to a method that detects a wider range of pyrogens than ever before.


Grow With Us

As part of the MAT Research team, you'll have the opportunity to grow, learn, and shape the future of ethical pyrogen testing.


Only apply if...


We’re Recruiting high performers! If you have the zeal for science, the drive to make a difference, and the passion to be a part of an evolving and revolutionary field, we want YOU.

Step into the future with MAT Research. Together, we'll create a world where ethical testing is the norm, not the exception.


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We have developed an improved Monocyte Activation Test (MAT) for pyrogen testing. The MAT serves as the replacement for the Rabbit Pyrogen Test and can be used to test parenteral drugs for endotoxin and non-endotoxin contaminations. Our technology uses cryopreserved pooled PBMC. This has made it possible to develop a MAT with both high sensitivity and robustness, ensuring reliability in the field.

Monocyte Activation Test (MAT) The Monocyte Activation Test (MAT) is a pyrogen test. MAT uses human blood cells to test for a fever reaction, mimicking the human immune reaction.The MAT serves as the replacement for the Rabbit Pyrogen Test and can be used to test parenteral drugs for endotoxin and non-endotoxin contaminations. Our technology uses cryopreserved pooled PBMC. This has made it possible to develop a MAT with both high sensitivity and robustness, ensuring reliability in the field. The MAT kit includes all the required consumables to perform the Monocyte Activation Test, making it convenient to perform. In addition to the kit we provide consulting services and technical support in setting up the MAT in your organisation.



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