Pharmaceutical Scientist/ Senior Technician

We are looking for an experienced Pharamaceutical Scientist/Senior Technician to support our progress towards clinical trials in some of the deadliest solid tumor diseases.

At OncoLize we develop injectable drug depots to 'Treat Tumors from the Inside. We target direct drug delivery to some of the most difficult to treat solid tumor diseases... and with success. (www.oncolize.com)

Our Product Platform ChemoGell™ is based on well-known polymers that can release a broad range of established Chemo drugs or peptides at high concentrations inside tumors, while sparring the body from the typical side-effects of Chemo...
And we aim at Triple A products: Affordable and Accessible for All.

Our start-up team is expanding as we approach our first clinical trials in Pancreatic Cancer. This is based on our initial successes in preclinical studies with LUMC (100% survival and no side-effects!) and other collaborations.

We currently focus on fine-tuning and finalizing our product-formulation and -processing before we hand it over to Contract Development Manufacturing Organisations.

Once that is done, we expand the portfolio to other Difficult-to-Treat solid tumor diseases by formulating other drugs and further tailoring the load and release characteristics of ChemoGell(TM).

The core technology team is established and running. Now we want to invite an experienced and self-starting pharmaCeuticcal Scientist/ Senior technician to the team to broaden our base and help us accelerate.

This is a great moment for you (and us!) to step in and help shape the future of our awesome product and company... and that ofthe patients we ultimately do it for.

Our start-up team is a mix of pharmaceutical-, polymer-, analytical science, with expert industrial and academic experiences in building companies and products.
Ambitious, Experienced, Passionate, Open minded, Dedicated.

Dutch, Belgian, Irish, Litowania and French so far. Today more women than men, but that's just who walks in the door, is curious, competent, ambitious and applies herself/himself/itself.

We collaborate closely with pre-clinical and clinical teams at LUMC and AUMC to target some of the deadliest tumor diseases, and that will expand to innovative pharma companies in the coming few years. You will start to interact with these pre-clinical and clinical experts as well.

What unites us is the promise and the opportunity that we can make these therapies much more efficient, with far less side-effects and affordable for patients and societies.

Ok, so your interested? What you will be doing initially:

·      Formulating prototypes, with characterization and drug release studies in the lab.

·      Setting up analytical methods, or making them up as we develop, and validating these.

·      Supporting our pre-clinical and clinical partners with samples and troubleshooting in their applications as the use our products. 

·      Optimizing processing steps before we hand them over to CDMOs, so documenting and putting these into SOPs.

·      Helping with patent applications.

·      Training and leading junior staff as we grow.

·      Organizing the lab in its formulation and analytical lay-out, equipment, maintenance, services... keeping the lab always running with smooth operations that your colleagues can take-over when you go on vacation.

What does it take for you to be successful and happy in this new job?

·      At least 3-5 years proven track record in Pharmaceutical science/ Formulation development with extensive analytical skills at drug development level, formulation development level, coming from a pharma-company or an established biotech.

·      It is essential that you have extensive experience with some of the following: UPLC/HPLC's, rheometer/viscosity/lyophilization/sterilization/ electronic data management, cGLP environment...

·      You have worked under cGLP, CMC, QA/QC and/or QBD. Methodical, attention for detail, clear and effective reporting, ‘Gung Ho’ if need be, not just communicating about success, but als about challenges you or we face.

·      Off course your education level is at applied technical or scientific level BSc. or MSc.

·      Most important is you attitude to get the job done, whatever it takes, because we will face challenges as team, and we need all hands on deck from time to time.

·      But you also need to be able to step back and think it through before you engage, ask and give input when needed.

We offer Euro 4.000-4.500 gross monthly to start with, depending on your experience and track record.

Sorry, no pension fund yet (should come later), but we do offer up to 3 months performance bonus at company level.

Holidays is 200 hours/year a full time job, next to public holidays, along with holiday allowance paid annually. 

Compensation for commuting 1st class, and once we can, we will pay for your sports or leisure subscription...

Training in advanced skills and knowledge will expand once we move into the clinical stages of the company (2027-2028).

Once you have demonstrated that you are part of our core team from year 3 onwards, you will be offered long-term success incentives such as options to shares...

You will be exposed to clinical trials, to collaborators in some of the most advanced drug development companies and academia that partner with us.

You can develop to lead small teams in product- or process development or manage the lab-operations altogether.

But like us, the biggest benefit may come from developing solutions to some of the most challenging cancer diseases that affect us all sooner or later... and keeping it affordable.

We hope it is clear this is not a starter's job at all. You really must demonstrate with your track record that you are up for this opportuinity and challenge... and that you are committed to such an impact opportunity.

Again, 3-5 years experience in a Pharma or Bio-tech operation, with strong preference in EU or USA. We will check your references. 

Once we move into our Series A funding round of €17 million, we may move from our top-quality Utrecht lab location to Leiden Bio Science Park, as this is where it all started...

And you must have an EU-working permit.

(Please don't apply if you don't comply, its just a waste of everybody's time)